No Image

Endogenization and excision of human herpesvirus 6 in human genomes

August 10, 2020 0

Summary: by Xiaoxi Liu, Shunichi Kosugi, Rie Koide, Yoshiki Kawamura, Jumpei Ito, Hiroki Miura, Nana Matoba, Motomichi Matsuzaki, Masashi Fujita, Anselmo Jiro Kamada, Hidewaki Nakagawa, Gen Tamiya, Koichi Matsuda, Yoshinori Murakami, Michiaki Kubo, Amr Aswad, Kei Sato, Yukihide Momozawa, Jun Ohashi, Chikashi Terao, Tetsushi Yoshikawa, Nicholas F. Parrish, Yoichiro Kamatani […]

No Image

Nitrogen coordinated import and export of arginine across the yeast vacuolar membrane

August 10, 2020 0

Summary: by Melody Cools, Simon Lissoir, Elisabeth Bodo, Judith Ulloa-Calzonzin, Alexander DeLuna, Isabelle Georis, Bruno André The vacuole of the yeast Saccharomyces cerevisiae plays an important role in nutrient storage. Arginine, in particular, accumulates in the vacuole of nitrogen-replete cells and is mobilized to the cytosol under nitrogen starvation. The […]

No Image

Immediate activation of chemosensory neuron gene expression by bacterial metabolites is selectively induced by distinct cyclic GMP-dependent pathways in Caenorhabditis elegans

August 10, 2020 0

Summary: by Jaeseok Park, Joshua D. Meisel, Dennis H. Kim Dynamic gene expression in neurons shapes fundamental processes in the nervous systems of animals. However, how neuronal activation by different stimuli can lead to distinct transcriptional responses is not well understood. We have been studying how microbial metabolites modulate gene […]

No Image

Mutation of CFAP57, a protein required for the asymmetric targeting of a subset of inner dynein arms in Chlamydomonas, causes primary ciliary dyskinesia

August 7, 2020 0

Summary: by Ximena M. Bustamante-Marin, Amjad Horani, Mihaela Stoyanova, Wu-Lin Charng, Mathieu Bottier, Patrick R. Sears, Wei-Ning Yin, Leigh Anne Daniels, Hailey Bowen, Donald F. Conrad, Michael R. Knowles, Lawrence E. Ostrowski, Maimoona A. Zariwala, Susan K. Dutcher Primary ciliary dyskinesia (PCD) is characterized by chronic airway disease, reduced fertility, […]

No Image

Drosophila miR-87 promotes dendrite regeneration by targeting the transcriptional repressor Tramtrack69

August 7, 2020 0

Summary: by Yasuko Kitatani, Akane Tezuka, Eri Hasegawa, Satoyoshi Yanagi, Kazuya Togashi, Masato Tsuji, Shu Kondo, Jay Z. Parrish, Kazuo Emoto To remodel functional neuronal connectivity, neurons often alter dendrite arbors through elimination and subsequent regeneration of dendritic branches. However, the intrinsic mechanisms underlying this developmentally programmed dendrite regeneration and […]

No Image

Replication of the Salmonella Genomic Island 1 (SGI1) triggered by helper IncC conjugative plasmids promotes incompatibility and plasmid loss

August 6, 2020 0

Summary: by Kévin T. Huguet, Nicolas Rivard, Daniel Garneau, Jason Palanee, Vincent Burrus The mobilizable resistance island Salmonella genomic island 1 (SGI1) is specifically mobilized by IncA and IncC conjugative plasmids. SGI1, its variants and IncC plasmids propagate multidrug resistance in pathogenic enterobacteria such as Salmonella enterica serovars and Proteus […]