AAV vector integration into CRISPR-induced DNA breaks

To design safe clinical trials, it is crucial to better understand and predict gene editing outcomes in preclinical studies. Bence György and collaborators have shown that adeno-associated viruses (AAVs) can stably integrate into CRISPR-Cas9-induced double-strand breaks, in up to almost half of the therapeutically targeted cells, in vitro and in vivo in mice. The team […]

What does the future of plastic look like?

Plastic waste is a growing problem around the world, despite efforts to recycle or reduce plastic use. In order to really transform the recycling process, more attention needs to be paid to the composition of plastic, according to a new research article from Lund University in Sweden. The paper presents strategies on how to improve […]

Synthetic cells make long-distance calls

The search for effective biological tools is a marathon, not a sprint, even when the distances are on the microscale. A discovery at Rice University on how engineered communities of cells communicate is a long step in the right direction. Read full news: Synthetic cells make long-distance calls

Taming the wild cheese fungus

The flavors of fermented foods are heavily shaped by the fungi that grow on them, but the evolutionary origins of those fungi aren’t well understood. Experimental findings offer microbiologists a new view on how those molds evolve from wild strains into the domesticated ones used in food production. Read full news: Taming the wild cheese […]

Mitochondria work much like Tesla battery packs, study finds

For years, scientists assumed that mitochondria—the energy-generating centers of living cells—worked much like household batteries, generating energy from a chemical reaction inside a single chamber or cell. Now, UCLA researchers have shown that mitochondria are instead made up of many individual bioelectric units that generate energy in an array, similar to a Tesla electric car […]